The immune system plays a central role in maintaining health throughout life. From its earliest development at birth to its gradual decline in later years, immune health is shaped by a complex interplay of biological, environmental, and lifestyle factors. This Resource Kit explores how immune resilience can be supported across every life stage, from neonatal immunity and childhood development to adolescent adaptation, adult maintenance, and the challenges of immunosenescence.

The kit highlights the importance of maintaining immune balance to prevent chronic inflammation, allergies, and autoimmune conditions. Strategies such as good nutrition, physical activity, mental health care, and timely booster vaccinations are discussed as essential tools for long-term immune support. Tailored vaccination approaches for each life stage—including maternal immunization and vaccine optimization for older adults—are also covered, emphasizing the importance of adapting immunization strategies to changing immune needs throughout the lifespan.

In today’s rapidly evolving public health landscape, Lifecourse Immunization stands out as a foundational strategy to protect populations, reduce healthcare burdens, and improve national preparedness. This approach emphasizes the value of vaccination across every stage of life—not just as an individual health intervention, but as a vital framework for national resilience and long-term community well-being.

This Resource Kit provides insights into why Lifecourse Immunization matters—from protecting vulnerable groups and easing pressure on healthcare systems, to reducing antibiotic use, safeguarding economies, and supporting global health security. It also outlines the critical components needed for effective policy implementation, including inclusive vaccination programs, public awareness, equitable access, and investment in vaccine innovation.